Subject of my diploma thesis is static and dynamic analysis of load bearing structure of tall concrete monolithic building. I specificly focusing on one dilatated part of architectural study called Centrum Bottova. Structure is being analysed by finite element metode in special software and is design to resist vertical and horizontal loads. During the structural analysis I tried to use inovative solutions and stick to architecture. Building consists of 2 undeground floors and 36 above-ground floors.I am not analysing the building only as a unit, I am also explicitly focusing on a analysis of a concrete floor, hybrid collumn and part of a stiffening core. Product of this analysis is design of reinforcement in this parts of strucuture by accepting construction principles. Structure is design on ultimate limit states and serviceability limit states.During analysis I am applying european standards and literature, the list is in a review of used literature.Thesis also consist of drawing documentation, calculations and reports located in the annexes of this diploma thesis.