The thesis deals with impact of parameter changes on simulation results of different tire constructions. In the introductory part, it describes tire history, its manufacturing process, construction, and different types of used tires. Afterwards it describes selected tire parameters and their further modifications. Further our thesis desribes the virtual tire model preparation process and settings for chosen simulations. We have also chosen specific tire type and created the suitable number of variants for our further studies. Our study will determine the impact of previously mentioned changes on the results of rolling resistance simulation and the footprint of the tire. All the simulation results are compared with real values provided by Continental.