The Master Thesis deals with design of hybrid ventilation in an administrative building. In the first chapter analyses it introduces current trends in the area of hybrid ventilation design in the buildings in Slovakia and around the world. The second chapter deal with principles concerning the hybrid ventilation design, exactly follow current regulations and standards, ventilation requirements, hybrid ventilation itself, as volume air flow rate, need for an hourly exchange, and the flow and drain of air, including the regulation of the entire hybrid ventilation system. Different modes of hybrid ventilation are also introduced. The next chapters bring a design of hybrid ventilation in an administrative building. The thesis closes with an evaluation of the design from the environmental and energy points of view.